Krüppel-like factor 4 (KLF4) has been implicated in vascular smooth muscle cell (VSMC) differentiation induced by transforming

mediated Smad and p38 MAPK Signaling in Vascular Smooth Muscle Cells Hui-xuan Li, Mei Han, Michel Bernier, Bin Zheng, Shao-guang Sun, Ming Su, Rui Zhang, Jian-ran Fu, Jin-kun Wen Department of Biochemistry and Molecular Biology, Key Laboratory of Neurobiology and Vascular Biology, China Administration of Education, Hebei Medical University, No. 361, Zhongshan East Road, Shijiazhuang, 050017, China College of Biology Science and Engineering, Hebei University of Economics & Business, Shijiazhuang, China Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA Running Title: KLF4 induces differentiation by TβRI To whom correspondence should be addressed: Department of Biochemistry and Molecular Biology, Hebei Medical University, No. 361, Zhongshan East Road, Shijiazhuang, 050017, China. Tel.: 86-31186265563; Fax: 86-311-86266180; E-mail: [email protected]